Renal cell carcinoma: Update on grading of chromophobe subtype
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چکیده
The image shows a chromophobe RCC that is a FNG 3 and the revised CTG 1 Impact of the new grading system on clinical outcome Several studies have shown the lack of prognostic utility of Fuhrman nuclear grade in chromophobe RCCs. Some even advocate not grading chromophobe RCCs due to the inaccuracy of the current FNG system in this tumor subtype. In fact, approximately 80% of all chromophobe RCCs are graded as FNG 3 and 4 (74% FNG 3). With the proposed system, 74% of the same chromophobe RCCs are grade 1. The new proposed chromophobe tumor grade proved to be a better predictor of clinical outcomes and had better correlation with tumor stage.
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Sarcomatoid Chromophobe Renal Cell Carcinoma with Heterologous Component
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